김영재 Young J Kim   교수 / D.D.S.， Ph.D.
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면역및분자미생물치의학 / 소아치과학교실 / 소아치과학
· Major : 치아우식학
· E-mail : neokarma@snu.ac.kr
· Tel : 02-2072-3080
· Laboratory : 치아우식학 연구실
Current Research Interests
Caiology
치아우식증은 인류에게 가장 만연하는 감염성 질환으로 mutans streptococci가 대표적 원인세균으로 알려져 있다. 원인균의 독력인자와 병인론에 관한 연구를 통해 치아우식증을 예방하고 조절하기 위한 다양한 방법을 개발

1. Individual caries risk assessment를 위한 tool의 개발과 이용

2. Mineral –interactive macromolecule과 pellicle precursor를 통한 치아표면의 biofilm의 형성과 caries의 pathogenesis

3. Mutans stereptococci의 virulence에 대한 molecular biological approach: potential utilization of molecular biological approaches in caries prevention

4. Cariostatic option으로서 vaccination
Research Methodology
1. Epidemiology: caries in young populations， early childhood caries(ECC) 2. Molecural biological approaches to caries: hydroxyapatite-interactive proteins and biofilm on tooth surface 3. Tooth gene expression and caries resistance
Publication / Patent
Quantitative real-time PCR for Streptococcus mutans and Streptococcus sobrinus in dental plaque samples and its association with early childhood caries， International Journal of Paediatric Dentistry. 19(2):141-147 ， 2009. DLX3 mutation in a new family and its phenotypic variations， J Dent Res， 87(4):354-357， 2008. Comparison of microleakage in sealant repaired with different surface treatment. KAPD 34; 204-213， 2007. Quantitative micro-CT evaluation of microleakage in composite resin. KAPD 34; 222-233， 2007. Gingival epithelial cell expression of macrophage inflammatory protein-1a induced by interleukin-1b and lipopolysaccharide， J Periodontol， 78(8): 1627-1634， 2007 The effects of collagenase and esterase on the microtensile bond strength in dentin bonding. JKAPD 34:285-291， 2007. Microtensile bond strength according to different dentin wall positions and curing lights in class I cavity of primary molar. KAPD 34: 62-72， 2007.