윤혜정 Hye-Jung Yoon   부교수 / D.D.S., Ph.D.
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구강병리학 / 구강병리학교실
· Major : 구강병리학(구강암, 타액선종양)
· E-mail : hyejyoon@snu.ac.kr
· Tel : 8772
· Laboratory : 구강병리학교실
Current Research Interests

1. 구강편평세포암종의 발생과 진행의 분자병리학적 기전

(Molecular mechanism of tumorigenesis and progression of oral squamous cell carcinoma)

- 구강편평세포암종의 발암과 전이에서 Cripto-1의 역할 및 신호전달체계 규명

2. 타액선암 감별진단의 표지자 및 예후 인자 개발에 관한 연구

(Development of diagnostic markers in the differential diagnosis and prognostic factors of salivary gland cancer)

3. 타액선암에서 염색체 이상과 유전자 증폭에 관한 연구

(Chromosomal abnormalities and gene amplification in salivary gland cancer)

Research Methodology
1. Tissue microarray(TMA)/ Immunohistochemistry 2. Fluorescence in situ hybridization(FISH)/ Silver enhanced in situ hybridization(SISH)/ Chromogenic in situ hybridization(CISH) 3. RNA in situ hybridization (RNAscope) 4. in vitro study: Treatment of recombinant protein/ Transfection with siRNA in oral squamous cell carcinoma(OSCC) cell lines
Publication / Patent
Choi YS, Kim Y, Yoon HJ, Baek KJ, Alam J, Park HK, Choi Y. The presence of bacteria within tissue provides insights into the pathogenesis of oral lichen planus. Sci Rep. 2016;6:29186. 

Shin WJ, Cho YA, Kang KR, Kim JH, Hong SD, Lee JI, Hong SP, Yoon HJ. KiSS-1 expression in oral squamous cell carcinoma and its prognostic significance. APMIS. 2016;124(4):291-8. 

Yoon HJ, Choe JY, Jeon YK. Mucosal CD30-Positive T-Cell Lymphoproliferative Disorder Arising in the Oral Cavity Following Dental Implants: Report of the First Case. Int J Surg Pathol. 2015;23(8):656-61.

Choi SY, Cho YA, Hong SD, Lee JI, Hong SP, Yoon HJ. Plasmablastic lymphoma of the oral cavity in a human imunodeficiency virus-negative patient: a case report with literature review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117(2):e115-20. 

Cho YA, Yoon HJ, Hong SD, Lee JI, Hong SP. A giant radiopaque mass in the masticatory space. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(5):566-70. 

Yoon HJ， Jo BC， Shin WJ， Cho YA， Lee JI， Hong SP， Hong SD. Comparative immunohistochemical study of ameloblastoma and ameloblastic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011; 112(6): 767-76.

Yoon HJ， Hong JS， Shin WJ， Lee YJ， Hong KO， Lee JI， Hong SP， Hong SD. The role of Cripto-1 in the tumorigenesis and progression of oral squamous cell carcinoma. Oral Oncol. 2011; 47(11): 1023-31. 

Yoon HJ， Cho YA， Lee JI， Hong SP， Hong SD. Malignant pigmented villonodular synovitis of the temporomandibular joint with lung metastasis: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011; 111(5): e30-6. 

Yoon HJ， Jayasooriya P， Hong SD， Lee JI， Hong SP. Clinico-pathologic conference: case5. Dentinogenic ghost cell tumour (DGCT). Head Neck Pathol. 2010; 4(4): 347-50. 

Yoon HJ， Hong SP， Lee JI， Lee SS， Hong SD. Ameloblastic carcinoma: an analysis of 6 cases with review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 108(6): 904-13.